Sixtyeight subjects with clinicopathologically diagnosed osmf were included in. Osmf is the most poorly appreciated and inadequately managed disease. The disease is rare in north america, and most cases seen in. Use of diode lasers in treatment of oral submucous. Management of oral submucous fibrosis by two different. Oral submucous fibrosis is defined as an insidious chronic disease affecting any part of the oral cavity and sometimes the pharynx. The available epidemiological data showed a clearcut geographical and ethnic predisposition, which suggested that certain customshabits prevalent among the population groups in southeast asia might be possible etiological factors. Surgical fibrolysis and skin grafts in the management of.
Aloe vera in the treatment for oral submucous fibrosis a. Pdf diode laser for treatment of osmf researchgate. This plays a role in the treatment of patients with oral submucous fibrosis because of its immunoregulatory effect. The disease is rare in north america, and most cases seen in migrants from south east asia or india. The treatment strategies sumit bhateja1, geetika arora2. The treatment of oral submucous fibrosis is a challenging task for a clinician. Oral submucous fibrosis is a chronic, complex, premalignant 1% transformation risk condition of the oral cavity, characterized by juxtaepithelial inflammatory reaction and progressive fibrosis of the submucosal tissues the lamina propria and deeper connective tissues. Management of oral submucous fibrosis by different. As the disease progresses, the jaws become rigid to the point that the person is unable to open the mouth. The treatment aims at good release of fibrosis and to provide long term results in terms of mouth opening. It was observed that oral zinc either alone or in combination with vitamin a or corticosteroids were found beneficial in the treatment of osmf. The suggested aetiological factor is the practice of certain customshabits of the inhabitants of south east asia. Management of oral submucous fibrosis by two different drug.
Oral submucous fibrosisa case report medcrave online. Management of oral submucous fibrosis with injection of. Latest treatmet modality of osmf is lasers, the hyaline bands are excised with the help of lasers which is a very good alternative to traditional surgical therapy but a bit costly and most of the osmf patients who have come to. The pathogenesis is obscure, and till date, no definitive therapy is available for the management of osmf. Review of drug treatment of oral submucous fibrosis. Pdf oral submucous fibrosis osf is often mocked as a condition. Successful use of inferiorly based nasolabial flaps in the management of oral submucous. Patient education and counseling is one of the foremost important step in the management of osmf which includes. This study was designed to determine the effect of pentoxifylline trental on the. We have mentioned all advanced treatments according to international standards slideshare uses cookies to improve functionality and performance, and to provide you with relevant advertising. Natural ayurvedic treatment of osmf along with life style modification can help in lowering the symptoms of osmf and may help in curing the disease.
Know all about the disease, including its possible causes, symptoms, diagnosis and treatment options. Instruct patients regarding the importance of discontinuing the habit of chewing betel quid. An approach to management of oral submucous fibrosis. Oral submucous fibrosis is a premalignant condition commonly prevalent in india, pakistan, taiwan and sri lanka. All the available treatment modalities give only symptomatic relief which are of short duration. Effectiveness of pentoxifylline in the treatment of oral. A total of 25 patients consented for surgical treatment. However, with the increase in immigration of people from the indian subcontinent, dental professionals in many developed countries will encounter this disease in the near future. Oral submucous fibrosis osmf is a chronic disorder seen only in persons who chew betel areca catechu nuts, pan masala or gutkha and is characterized by tightening of the buccal, and sometimes palatal and lingual mucosae, causing trismus. Classification based on clinical features of osmf chandramani more et al 2011 m1 interincisal mouth opening up to or greater than 35 mm. Oral submucous fibrosis osmf is a highrisk precancerous condition characterised by slowly progressive chronic fibrotic disease of the oral cavity and oropharynx, in which the oral mucosa loses its elasticity and develops fibrous bands, which ultimately leads to difficulty in opening the mouth. Oral submucous fibrosis osmf is a highrisk premalignant condition predominantly seen in the indian subcontinent. Role of collagen membrane in the treatment of advanced.
The disease has a high malignant potential and thus should be diagnosed and treated at the earliest. One new treatment modality which is gaining recognition is the use of turmeric in osmf. Treatment of osf is difficult, as not many large, randomized controlled trials have been conducted. Oral submucous fibrosis and the role of curcumin in its treatment. Patients with osmf need treatment for trismus correction, reconstructive surgery for. The incidence of osmf still rising alarmingly and there is. Total of 30 patients with clinically diagnosed osmf patients. Oral submucous fibrosis osf is a precancerous condition of the oral mucosa. Definition it is an insidious chronic disease affecting any part of the oral cavity and sometimes the pharynx. The aim of the present study was to compare the efficacy of spirulina and lycopene in the management of osmf.
Curcumin is the principal curcuminoid and comprises approximately 25% of turmeric. Oral submucous fibrosis osmf is a chronic disease of insidious onset and a prevailing potentially malignant disorder characterized by juxtaepithelial inflammatory reaction along with mucosal fibrosis. M2 interincisal mouth opening between 25 and 35 mm m3 interincisal mouth opening between 15 and 25 mm m4 interincisal mouth opening less than 15 mm. Patients characteristically exhibit progressive reduction in mouth opening. Turmeric curcuma longa linn is the perennial plant, when dried rhizomes, it is made into a yellow powder with a bitter yet sweet taste. A wide range of treatment including drug management. Several glucocorticoids are used for the treatment of osmf, short acting.
R crri,saveetha dental college and hospitals, chennai abstract. The progressive irreversible fibrosis of the submucosa causes trismus, an inability to consume the average spicy food that people in the subcontinent are accustomed to, and carries a high risk of malignant transformation 1. Pdf non surgical approaches in treatment of osf researchgate. Oral submucous fibrosis osmf is a potentially malignant disorder of the oral mucosa, mainly associated with the practice of chewing gutka and betel quid. Oral submucous fibrosis osmf is a potentially malignant disorder largely seen in the southasian countries where areca nut is found to be the main predisposing factor. Oral submucous fibrosis osmf is a persistent, progressive, precancerous condition of the oral mucosa, which is related with betel quid chewing habit. All patients were males and their ages ranged from 21 to. Oral submucous fibrosis and the role of curcumin in its. In 1952, schwartz coined the term atrophica idiopathica mucosa oris to describe an oral fibrosing disease he discovered in 5 indian women from kenya. Oral submucous fibrosis osmf, a precancerous condition of the oral cavity, has been studied by a number of workers in the field. The oral submucous fibrosis osmf as defined by pindborg and sirsat as an insidious chronic fibrotic disease that involves the oral mucosa and occasionally the pharynx and upper third of oesophagus. Laser treatment video for oral submucous fibrosis part.
Evaluation of efficacy of turmeric in management of oral. Oral submucous fibrosis is a chronic disease characterised by progressive inability to open the mouth. Pentoxifylline, a methylxanthine derivative, has vasodilating properties and is believed to increase the vascularity of the mucosal layer. Advanced treatment of oral submucous fibrosis by dr.
Gupta s, jawanda mk, arora v, mehta n, yadav v, role of lycopene in preventing oral diseases as a nonsurgical aid of treatment, int j prev med, 6, 2015, 70. Classification system for oral submucous fibrosis jiaomr and predominantly aimed at improving mouth movements. Medical and surgical treatment options for oral submucous. Osmf is characterized by deposition of dense collagen. Oral submucous fibrosis osf is the chronic debilitating and crippling condition of. All the documented treatment modalities, ranging from medicinal treatment to surgical treatment are purely symptomatic in nature and total cure of the disease is still elusive. Index definition history keywords pathogenesis clinical features laboratory findings classification treatment 3. Most treatment modalities in osmf have centered on relief of the burning sensation and release of the fibrotic bands to improve mouth opening.
Complete details of surgery were explained to the patients and informed consent was obtained from each patient. Different authors have suggested variety of treatment. Joshi subsequently coined the termed oral submucous fibrosis osf for the condition in 1953. Oral submucous fibrosis osmf is an insidious chronic progressive disease of the oral cavity which is considered as a precancerous condition. Oral submucous fibrosis osmf is a potentially malignant disease that results in progressive juxtaepithelial fibrosis of the oral soft tissues. Various local grafts have been used to cover the buccal mucosal defects after the fibrotic bands are released in oral submucous fibrosis. Oral submucous fibrosis osmf, now labeled as a potentially malignant disorder, is rather unique in its clinical presentation. Unusual complication of intralesional corticosteroid in. The principal actions of drug therapy include antifibrotic, anti. Pdf an approach to management of oral submucous fibrosis.
Use of nasolabial flap in the management of oral submucous. Oral submucous fibrosis osmf is a chronic debilitating and potentially malignant. Betel nut and pan are freely available in the united kingdom, and in a city such as leicester, one might expect to find 3000 cases of oral submucosal fibrosis. There was improvement in the symptoms of all the patients. As the disease progresses, the oral mucosa becomes stiff due to the formation of fibrotic bands in the cheek, ultimately leading to. The pathogenesis is poorly understood and the disease is difficult to treat.
Scribd is the worlds largest social reading and publishing site. Capsaicin, an active principle, mild irritant, which brings about epithelial and connective tissue changes in osmf patients. The awareness of such a condition among oral physicians can help in timely diagnosis and thus appropriate treatment can be administered depending on the degree of involvement. Comparative efficacy of newer antioxidants spirulina and.
These are injected into the fibrotic bands weekly for 68 weeks with regular monitoring of mouth opening. Oral submucous fibrosisa new treatment regimen joms. Oral submucous fibrosis osf is an extremely discomforting oral condition that is marked by the development of painful lesions inside the mouth that refuse to go away on their own. Various treatment modalities are available for its management, but these have largely been ineffective. Research article assessment of utility of tulsi and. Oral submucous fibrosis is a high risk precancerous lesion which predominantly affects indians, indians in diasporas, to a lesser extent in other asiatic, and sporadically in europeans. A wide range of treatment including drug therapy, surgical therapy, and physiotherapy have been attempted till date, with varying degrees of benefit, but none have been able to cure this disease. Treatment options for oral submucous fibrosis iosr journal. Elastic degradation of collagen and ultrastructurally, partial or complete degeneration of collagen into elastin. The study aimed to evaluate the efficacy of spirulina along with different physiotherapeutic modalities in the management of osmf. Several classifications based on clinical and histological features, have been put forth by various researchers, based on different aspects of osmf. Oral submucous fibrosis is a chronic insidious disease which was previously designated as a premalignant condition but presently categorized under potentially malignant disorders who 2005. Successful treatment of oral submucous fibrosis with local injections of chymotrypsin, hyaluronidase, and dexamethasone is reported. Unusual complication of intralesional corticosteroid in oral submucous fibrosis patient srikanth g 1, komal s 2, jyotsna r 1 and kalyana c.
A wide range of treatment modalities have been tried ranging from medical, physical, or surgical interventions, but combinations of these have shown better results. The early form of the disease can be treated by medicinal means, however, advance stages needs surgical excision of the fibrotic tissue bands. Oral submucous fibrosis osf is a chronic condition almost exclusively occurring among indians and to a lesser extent in the other asiatic people. Osmf is associated with immunological changes altered levels of serum immunoglobulins and the effect of treatment especially antioxidants and levamisole on serum ig is not known. Osmf is a chronic condition of the oral cavity which results in permanent disability. A read is counted each time someone views a publication summary such as the title, abstract, and list of authors, clicks on a figure, or views or downloads the fulltext. Recent advancements in oral submucous fibrosis management. Ifngamma, through its effect of altering collagen synthesis, appears to be a key factor to the treatment of patients with oral submucous fibrosis. Pdf aloe vera in the management of oral submucous fibrosis. The study concludes that aloe vera can be an alternative, safe, and effective treatment regime in the management of oral submucous fibrosis. Oral submucous fibrosis an overview sciencedirect topics. Oral submucous fibrosis causes, symptoms, treatment and.
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